This is the eleventh FA Cup tie between Manchester United and Chelsea; The Red Devils lead the head-to-head record by eight wins to two, although Chelsea did win the last meeting (the 2007 final).
The only previous sixth round meeting between United and Chelsea in the FA Cup is also the only previous tie between the sides to go to a replay; after a 0-0 draw at Old Trafford, the Red Devils won 2-0 at Stamford Bridge to progress in their treble winning season (1998/99).
The Red Devils have won their last two FA Cup games at Stamford Bridge (2-0 in 1999 and 5-3 in 1998); they last lost there in this competition in March 1950.
The last seven meetings between these sides in all competitions have seen 34 goals scored, with 18 netted in just two meetings so far this term.
Javier Hernandez has scored in six of the last seven meetings between the Red Devils and the Blues.
Chelsea have only lost one of their last 39 FA Cup games outright, winning 31 and drawing seven.
Indeed, the Blues are now unbeaten in 28 FA Cup games (excluding penalty shootouts), the longest ever run without defeat by a single side.
Juan Mata has scored five goals and assisted eight in just 11 appearances in the FA Cup.
Sir Alex Ferguson's side have scored in each of their last 10 away FA Cup games, netting more than once in nine of those outings (26 in total).
The Blues have not lost an FA Cup game at Stamford Bridge since March 2003 (W20 D4) and have scored in each of their last 33. However, this last defeat (versus Arsenal) was the last quarter-final replay that they played at home.
Indeed, Manchester United were the last team to prevent Chelsea from scoring in an FA Cup game on their own patch, beating them 2-0 in a sixth round replay in 1999.